Malondialdehyde and Nitric Oxide Levels in Erythrocytes from Patients with Systemic Sclerosis

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Malondialdehyde and nitric oxide levels in erythrocytes from patients with systemic sclerosis.

OBJECTIVE To investigate malondialdehyde (MDA) and nitric oxide (NO) levels in the erythrocytes from patients with systemic sclerosis (SSc). SUBJECTS AND METHODS Twenty-nine patients diagnosed as having SSc and 16 volunteer healthy subjects (as control group) participated in the study. Fasting blood samples were obtained from the patients and healthy subjects in anticoagulated tubes (with EDT...

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Malondialdehyde, glutathione, and nitric oxide levels in Toxoplasma gondii seropositive patients.

The aim of this study was to investigate the difference in the serum malondialdehyde (MDA), glutathione (GSH), and nitric oxide (NO) levels between normal and T. gondii-infected patients. To this end, MDA, GSH, and NO levels in the sera of 37 seropositive patients and 40 participants in the control group were evaluated. In Toxoplasma ELISA, IgG results of the patient group were 1,013.0 +/- 543....

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Decreased nitric oxide in the exhaled air of patients with systemic sclerosis with pulmonary hypertension.

BACKGROUND Systemic sclerosis (SSc) may be complicated by pulmonary hypertension (PHT), which can occur both in the setting of fibrosing alveolitis or as lone pulmonary vascular disease. Nitric oxide (NO) is a powerful vasodilator and is produced by various cells in the respiratory tract including pulmonary vascular endothelial cells and can be measured in expired air. A study was undertaken to...

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Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine.

OBJECTIVES Endothelial dysfunction is a primary event in systemic sclerosis; however, the aetiology of events and the role of nitric oxide (NO) is still unclear. The aim of the present study is to investigate whether there are abnormalities in NO metabolism in plasma from patients with primary Raynaud's phenomenon (RP) and in the pathogenesis of systemic sclerosis (SSc): limited SSc (lSSc) and ...

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ژورنال

عنوان ژورنال: Medical Principles and Practice

سال: 2008

ISSN: 1423-0151,1011-7571

DOI: 10.1159/000129620